28 Feb PT-141 Peptide As A Potential Treatment for Erectile Dysfunction and Hypoactive Sexual Desire?

What is PT-141, and how does it work?

PT-141 is a peptide, a chain of amino acids, the basic building blocks of our bodies, but more specifically, PT-141 is an artificial melanocortin activator. This means that it is a drug that acts on the central nervous system to produce a response in the body.

In this case, the peptide acts on the central nervous system to produce an erection and improve sexual desire and performance.

The drug mimics a substance that the body produces naturally, but often in insufficient quantities, and can reliably produce an erection for a set period, depending on the dosage given.

It is an effective drug for men with emotional or mental conditions that cause erectile dysfunction rather than physical causes of ED. Further research shows that the peptide may be an alternative to standard ED medications like Viagra, which can’t be taken by men with heart problems because, unlike other drugs which act on the vascular system, this drug acts solely on the central nervous system. While most other medications to treat erectile dysfunction are given via an oral pill, PT-141 is an intranasal injection given in the nose.

How effective is PT-141 at treating ED and hypoactive sexual desire?

We will discuss each condition in detail to determine how effective the peptide is at treating each one.

Erectile dysfunction

Studies were conducted first in animals and then in control groups of men with mild to moderate ED using different doses of the drug PT-141. In the first study, it was found that a majority of the participants in the study reported spontaneous erections that lasted between 26 and 53 minutes without noticeable side effects.¹

Furthermore, participants in the study were found to be able to achieve erection via stimulation versus simply waiting for the medication to take effect.

The data also showed that erections could be sustained for the entire activation period (up to the 53-minute mark) without fail, meaning the medication achieved reliable erections each time. A second study confirmed similar results when testing multiple control groups, including healthy men with no ED, men who responded well to other ED medication, and men who were not responsive to ED medication. In all cases, the men could achieve some form of rigid erection depending on dosage, with the non-responsive group having the shortest erection time.

Hypoactive sexual desire

A study was conducted using a group of premenopausal women over 52 weeks using PT-141.² All trial participants who completed the study noted statistically significant increases in sexual drive compared to the placebo group. They also noted less stress related to low sex drive.

Throughout the study, the positive increase in sexual drive continued to rise as the stress from having a low sex drive decreased.

While the results of the study were conclusive, several participants dropped out of the study due to adverse side effects. However, the only side effects noted in the study were nausea, flushing, and headache. Data on potential severe and long-term side effects are not yet available.

Are there any side effects to PT-141?

Like any medication, there is the potential for some side effects. Patients allergic to the drug or who experience an allergic reaction should contact their doctor immediately. The most common side effects of the drug include:

• nausea (most common after the first dose and usually lasts for about 2 hours)
• vomiting
• headache
• flushing
• nasal stuffiness

• cough
• tiredness
• dizziness
• pain, redness, bruising, itching, numbness, or tingling in the area where the medication was injected

The following severe side effects have been cited in rare cases:

• Increased blood pressure and heart rate that lasted up to 12 hours

The exact cause of this side effect is unknown. Still, you should talk to your doctor immediately if you experience this or any other serious side effects after taking the medication.

How can I get PT-141?

PT-141 is a prescription medication that should only be given by a licensed medical professional. It is important to only take the medication under the supervision of a doctor to prevent adverse events. Some medical sites and other avenues may claim to be able to provide the drug to patients, but this is highly unsafe and should not be attempted.

Your doctor will need to perform a health evaluation before deciding if PT-141 is the right treatment for you.

Conclusion

If you have suffered from ED or a low sex drive and other treatments and medications have failed, then now is the time to talk with your doctor about PT-141 and whether it is the right choice. Clinical studies have shown marked improvements for men with erectile dysfunction, including spontaneous erections. Women with hypoactive sexual desire have been shown to have increased sexual desire and lower stress from taking the medication.

General side effects are mild, but long-term data is not yet available for the drug. Talk with your doctor about any medications you may be on and any health concerns you may have before beginning treatment with PT-141.

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