Enclomiphene Therapy

Enclomiphene is a convenient oral tablet that stimulates your body’s own natural testosterone production and helps you feel your best.

Enclomiphene Subscription

Our Enclomiphene subscription delivers convenient, in-home treatments directly to your door. Enclomiphene has undergone extensive clinical studies and is scientifically proven to be effective in stimulating the production of testosterone. [1]

By acting on the hypothalamus and pituitary glands, it helps restore the natural balance of hormones in your body, leading to increased testosterone levels. [2]


  • Order for comprehensive hormone lab testing
  • Virtual consultation with our medical provider to determine your eligibility
  • Hormone replacement kits shipped directly to you

Does not Include: 

  • Cost of labs (covered by most PPO insurances)


Monthly Subscription: $199/month

How Does Enclomiphene Therapy Work?

If you have been looking for an alternative to testosterone supplementation, you may have come across enclomiphene in your research. It acts as a selective estrogen receptor modulator (SERM), affecting the hypothalamus and subsequently increasing testosterone production. Keep reading for more information regarding enclomiphene to help you decide if it is the right treatment for you.

Clomiphene vs. Enclomiphine: What’s the difference?

As you look for information regarding enclomiphene, you will often see information regarding clomiphene, also known by its brand name Clomid. Clomiphene is a combination of zuclomiphene, a weak estrogen agonist, and enclomiphene. It is used to treat infertility in women and was also studied for its benefits for men. Later in this article, we will review research that has shown enclomiphene can have more benefits for men than clomiphene.

Benefits of Enclomiphene

The benefits of enclomiphene stem from its ability to help increase testosterone levels. While many men choose to supplement testosterone, it comes at a price – testosterone supplementation often causes infertility. Enclomiphene, on the other hand, has been proven to address hypogonadism while preserving sperm count. In one 2015 study, enclomiphene therapy resulted in more significant and sustained increases in testosterone for patients than testosterone gel therapy. It also offered larger and more consistent decreases in cholesterol.

In the same 2015 study, testosterone supplementation resulted in a 32%-56% drop in sperm counts, vs. an 11%-15% drop in those taking enclomiphene. Another 2023 study involving a comparison of clomiphene and enclomiphene revealed that while both treatments resulted in increased testosterone, only those who took enclomiphene experienced a significantly higher motile sperm count. These benefits for male fertility were further reinforced by an April 2023 study in which enclomiphene was linked to higher pregnancy rates in comparison to clomiphene.


Lean muscle mass & less body fat

Treating hypogonadism can help increase lean muscle mass and decrease body fat. Studies demonstrate that men with low T who increased testosterone levels lost fat and increased muscle size; however, there have been mixed results in whether these changes also increased strength. A study of obese men found that increased testosterone resulted in higher losses of fat and sustained more lean muscle mass than diet and exercise alone.

Sexual performance, drive, & libido

The effects of fatigue and lack of energy stemming from hypogonadism also affect sexual performance and drive. Those who experience low testosterone frequently complain of a loss of libido. Studies show that bringing testosterone levels back to normal help reverse low libido and energy levels, and other related symptoms, which can help restore sexual performance.

Sexual performance, drive, & libido

The cardiovascular benefits of restoring testosterone levels can help improve athletic performance. Keeping the heart healthy facilitates the delivery of oxygen to muscles and organs, which is necessary for the body to achieve peak performance. Paired with the other effects of increased testosterone, including improved mood and cognition, increased energy, and increased muscle mass, treatment can substantially help in achieving health goals.

These effects can also help support overall health as well – a study involving 83,000 veterans found that those treated for low testosterone were 56% less likely to die during the 4-6 year follow-up period, were 24% less likely to experience heart attack, and 36% less likely to have a stroke.

It’s important to note that enclomiphene treatments work best when paired with healthy lifestyle changes. Increasing testosterone is not a substitute for healthy diet and exercise. It instead is intended as a tool to increase the effects of a mindful lifestyle to help you achieve your health and fitness goals faster and more efficiently.

Although enclomiphene is not currently FDA-approved as treatment for low testosterone, there is evidence that it is effective in offering the benefits reviewed above. A review of enclomiphene in 2022 offered patient testimonials citing benefits for energy, libido, mental health, and lower cholesterol.

Energy, focus, productivity, & confidence

Research indicates that higher testosterone has been linked to a reduced risk of Alzheimer’s disease. Treatments to address hypogonadism have also been linked to improvements in spatial memory, verbal memory, and faster processing speeds.

The loss of testosterone that comes with aging can have significant negative impacts on day-to-day experiences. Some of the most prominent symptoms reported are fatigue, low energy levels, and difficulty concentrating. Bringing testosterone levels back to normal combats these effects, helping those struggling with hypogonadism to regain the confidence, energy, and focus necessary to tackle each day.

Prime optimal health, well-being, & mood

The effects of hypogonadism overlap with symptoms of depression, and it’s not difficult to understand why once you take the other symptoms of decreased testosterone into account. Fatigue, loss of energy, difficulty concentrating, and loss of libido can significantly impact day-to-day life.

Men who have low T often report feeling irritable as well, which negatively impacts personal relationships as well, leading to an unhealthy cycle that can take a toll on mental health. Combating these symptoms by restoring testosterone can improve overall mood and well-being, and may be effective in helping treat depression.

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Signs of Low Testosterone

  • Decreased muscle mass & strength
  • Increased body fat
  • Low libido & sexual function
  • Erectile dysfunction
  • Fatigue & low energy
  • Difficulties with concentration & memory
  • Sleep disturbances & insomnia
  • Depressed mood & irritability
  • Decreased sense of well-being

Potential Side Effects

Studies of enclomiphene are still in progress, and thus there is no information on the long-term effects of enclomiphene at this time. However, studies of the drug so far show that it is overall well-tolerated, causing few side effects.

Some of the more common side effects of enclomiphene include:

  • Headache
  • Nausea
  • Diarrhea
  • Common Cold
  • Hot flush
  • Joint pain
  • Dizziness

Are there any serious side effects of enclomiphene?

As previously stated, more studies are necessary to determine the long-term effects of enclomiphene. While enclomiphene is typically a safe treatment to address hypogonadism without impacting fertility, it’s important to consult an experienced doctor before beginning treatment.

A licensed and trained healthcare professional should conduct an evaluation of your current health, including medications and other conditions you may have, as well as your family health history before prescribing enclomiphene. A doctor’s guidance is also necessary in obtaining enclomiphene to ensure that your treatment is safe. Obtaining treatments from a reputable source ensures that ingredients are high-quality and have been formulated according to rigid standards to avoid contamination.

Overall, enclomiphene is a promising treatment for those who wish to address hypogonadism while maintaining fertility. Enclomiphene appears to boost testosterone production without raising cholesterol levels or posing the cardiovascular risks associated with drugs such as Viagra. However, as with any treatment, those interested in enclomiphene should be sure to get the guidance of a licensed and trained healthcare professional before taking enclomiphene.

Other potential side effects

Because clomiphene has been studied more intently, and enclomiphene is one of its active ingredients, researchers often consider the side-effects of clomiphene when evaluating a patient for enclomiphene. They will also take the side effects of increased testosterone into consideration.

Some of these side effects include:

  • Muscle spasms
  • Fatigue
  • Increased appetite
  • Vision blurred
  • Aggression
  • Irritability
  • Acne
  • Allergic Reaction

How it Works

Health Check & Lab Test

Book an in-home lab draw or walk into any Quest near you for lab testing.

Virtual Consultation

Online consult with your medical provider.

Shipped To You

Enclomiphene oral tablets shipped directly to you.


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    Frequently Asked Questions

    What is Enclomiphene?

    Enclomiphene is a medication specifically designed to help men increase their testosterone levels. It acts on the hypothalamus and pituitary glands to stimulate testosterone production.

    Who can benefit from using Enclomiphene?

    Enclomiphene is beneficial for men who have low testosterone levels and are experiencing symptoms such as fatigue, decreased libido, decreased muscle mass, and mood changes.

    What are the benefits of Enclomiphene?

    • Increased Testosterone Levels: Enclomiphene is specifically designed to stimulate testosterone production in men, helping to address low testosterone levels and its associated symptoms. By boosting testosterone, it can lead to improved energy levels, increased libido, enhanced muscle mass, and better overall well-being.
    • Improved Sexual Function: Low testosterone levels can affect sexual function, leading to decreased libido and erectile dysfunction. Enclomiphene can help restore healthy testosterone levels, resulting in improved sexual desire and performance.
    • Enhanced Mood and Mental Well-being: Testosterone plays a crucial role in mood regulation and mental well-being. By increasing testosterone levels, Enclomiphene may contribute to improved mood, reduced fatigue, increased motivation, and enhanced cognitive function.
    • Increased Muscle Strength and Mass: Testosterone is essential for muscle growth and strength. Enclomiphene can support the development of lean muscle mass and help individuals achieve their fitness goals by improving muscle strength and promoting efficient workouts.
    • Weight Management Support: Low testosterone levels have been linked to weight gain and difficulty in losing weight. By boosting testosterone, Enclomiphene may help individuals manage their weight more effectively and support a healthy body composition.
    • Potential Improvement in Bone Density: Testosterone is important for maintaining healthy bone density. Enclomiphene, by increasing testosterone levels, may help support bone health and reduce the risk of osteoporosis.
    • Potential Positive Impact on Cardiovascular Health: Research suggests that optimal testosterone levels may contribute to cardiovascular health. Enclomiphene’s ability to increase testosterone may have a positive impact on factors such as blood pressure, cholesterol levels, and overall cardiovascular well-being.

    How does Enclomiphene work to increase testosterone levels?

    Enclomiphene acts as a selective estrogen receptor modulator (SERM). By blocking estrogen’s negative feedback on the hypothalamus and pituitary glands, it increases the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which, in turn, stimulates testosterone production.

    Is Enclomiphene safe for men to use?

    The adverse effects of enclomiphene have been extensively studied during phase II and phase III clinical trials. The drug is generally well tolerated, however infrequent side effects may occur such as:
    — Headache (observed in 3.3% of patients)
    — Nausea (observed in 2.1% of patients)
    — Diarrhea (observed in 1.9% of patients)
    — Common Cold (observed in 1.7% of patients)
    — Hot flush (observed in 1.7% of patients)
    — Joint pain (observed in 1.2% of patients)
    — Dizziness (observed in 1% of patients)

    Are there any side effects associated with Enclomiphene use in men?

    Some men may experience side effects while using Enclomiphene, although they are generally mild and temporary. Common side effects may include hot flashes, mood swings, headaches, and nausea. However, not everyone experiences these side effects.

    How long does it take to see results with Enclomiphene?

    The timeframe for seeing results with Enclomiphene can vary depending on the individual. Some men may notice improvements in symptoms within a few weeks, while others may take longer. It is important to follow the recommended treatment plan and consult with your healthcare provider for guidance.

    Can Enclomiphene be used alongside other medications or supplements?

    It is crucial to inform your healthcare provider about all medications and supplements you are currently taking. They can determine if Enclomiphene is suitable to use alongside other medications or if any adjustments are necessary.

    How do I take Enclomiphene?

    Enclomiphene is typically taken orally in tablet form. The dosage and frequency will be determined by your healthcare provider, so it is important to follow their instructions carefully.

    Can Enclomiphene guarantee an increase in testosterone levels?

    While Enclomiphene is designed to increase testosterone levels, individual responses may vary. Success rates depend on various factors, including underlying health conditions and individual metabolism.

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