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How Often Should You Receive NAD Injections?

NAD (Nicotinamide Adenine Dinucleotide) therapy is gaining wide attention for its potential overall well being benefits in addition to its role in anti-aging, mood and metabolism regulation, brain function as much more. NAD injections offer fast absorption of NAD+ into the bloodstream for fast absorption. 

NAD+ injections offered by ConciergeMD enable you to self-administer a medical recommended dose in the privacy and comfort of your own home. After consultation, supplies of the recommended dosage and everything needed for safe injections are delivered.

So, what is NAD and how often should you receive NAD+ injections? Let’s get into it.

What Is NAD and Why Is It Important?

NAD, or Nicotinamide Adenine Dinucleotide) is a molecule important in the health of your body’s cells. Maintaining healthy levels of NAD can have positive impacts on your overall health and wellness. NAD plays several key roles: 

  • Converts nutrients into energy adenosine triphosphate production, also known as ATP or your body’s energy currency
  • Supports mitochondrial function[1]
  • Repairs DNA damage
  • Regulates cell aging via sirtuins, a protein involved in regulating cellular processes including the aging and death of cells, and their resistance to stress.
  • Impacts neurotransmitter production (impacting mood and cognition)

There are several types of NAD therapy that can provide the anti-aging, energy, brain function, detox and addiction support benefits, and lessen the effects of chronic fatigue.

  • IV (intravenous)
  • Injections
  • Oral Supplements
  • Nasal Spray

For this article, we’ll focus on NAD injections.

How Often Should You Take NAD Injections?

The frequency of NAD injections will vary by individual. Additionally the frequency will depend on whether the NAD is to replenish levels to meet overall health goals or if used for more intensive purposes. Below are some general guidelines that you can discuss in a personal consultation with a ConciergeMD medical staff member.

  • General Wellness or Anti-Aging: 1-2 times per week to support energy, cognitive function, and cellular repair in middle-aged or older adults.
  • For Detox, Addiction Recovery, or Chronic Fatigue: Daily for 4-10 days at the start of therapy. In these situations, the program starts with intensive loading followed by a tapering to weekly or monthly.
  • For Athletic Recovery or Performance: A typical regimen may include 1-3 times per week during periods of high training or recovery. It may also be used for short-term performance boosts or injury recovery.

How to Determine the Right NAD Frequency for You

Determining the right frequency of NAD injections is not one-size-fits-all. Many factors have to be considered to determine a frequency schedule personalized for each individual. Factors include age, health status, symptoms, and lifestyle habits. 

A medical consultation with a medical professional at ConciergeMD is the first step in determining the frequency of NAD injections that is right for you. Once you speak with a ConciergeMD medical staff member, a personalized treatment plan can be developed. 

A ConciergeMD therapy plan begins with a comprehensive health assessment with a member of our medical staff. This assessment provides an evaluation of your health needs and goals. We also consider your lifestyle factors (diet, exercise and stress levels). Your health goals are also considered; whether you are aiming for enhanced energy, cognitive function, or recovery support are all factors in adjusting the right therapy for you.

How Long Does It Take for NAD Injections to Work?

Once injected, NAD⁺ or its precursors are rapidly absorbed into cells, where they are used or stored. Even though NAD+ is rapidly used by your cells, its therapeutic benefits can last much longer. This table outlines the short-term and long-term effects and benefits for the various uses of NAD+ injections.

Benefit Category

Energy Boost

Cognitive Clarity

Anti-Aging Effects

Detox Support

Timeframe

Hours-Days

Days-Weeks

Weeks-Months

Immediate-10 Days

Notes

Often observed after firsts injection

Improves with cumulative doses

Requires long-term consistent use

Used in high-dose situations

After 1- 2 hours

Positive effects after the first NAD+ injection may be felt within 1-2 hours, especially if NAD levels were low to start with. Positive effects include:

  • Increased alertness or mental clarity
  • Mild energy boost
  • Improved mood or calmness
  • Reduced brain fog

Within 24-48 hours

  • Smoother, more sustained energy (as opposed to the jittery energy from caffeine)
  • Elevated mood and motivation
  • Enhanced focus and cognitive function
  • Deeper sleep that night in some cases

Can You Take Too Much NAD?

Use of NAD is generally safe. Excess NAD is naturally excreted in urine. Overuse of NAD can lead to mild, short term effects which are often dose-dependent and more likely when doses are high or administered too rapidly. 

Short term effects may include:

  • Headaches
  • Dizziness or lightheadedness
  • Brain fog (rare)
  • Irritability or mood swings. 
  • Flushing or hot flashes
  • Rapid heartbeat
  • Chest tightness
  • Nausea or upset stomach
  • Muscle or abdomen cramping

Many of these effects can be mitigated by staying hydrated before and after the injection, eating a light meal beforehand, rest, and avoiding intense activity immediately after.

Your initial consultation with ConciergeMD is an important part of your treatment plan because it will determine your initial dosage and regimen for your at-home injections. Injection instructions are reviewed at this time and are also included with your home shipments. 

While day-to-day administration is done by the individual, ConciergeMD provides ongoing support through virtual consultations. These follow-up appointments allow for a discussion about your progress, concerns, and when adjustments to your personal treatment plan can be made. With this collaborative approach, you can be assured that the treatment stays aligned with your health objectives.

Get Your NAD Injections Today

Whether your goals include anti-aging, better cognitive function, enhanced energy and mood, addiction support, or recovery from athletics, a regular regimen of NAD injections may be right for you. A first step is a consultation with ConciergeMD to determine the dose and frequency needed to meet your health goals. 

Frequently Asked Questions

How Often Should I Take NAD Therapy?

The frequency depends on many factors including your current health status, diet, lifestyle and well-being goals. A consultation with a ConciergeMD medical expert will aid in preparing a personalized treatment plan.

Can I Get NAD Injections at Home?

Yes. NAD injections can be shipped directly to your home with everything you need to self-administer NAD.

Is NAD Safe for Long-Term Use?

NAD is generally safe. However, long-term use should always be under supervision of a medical expert. 

What’s the Best Time of Day to get NAD Injections?

Receiving NAD injections is recommended for the morning or mid-afternoon for several reasons. You will have the mental clarity and energy for the day ahead, it avoids potential sleep disturbances from late-day energy, and it aligns with the body’s circadian rhythm alignment and natural cortisol patterns; the latter is highest in the morning. For physical activity recovery or fatigue from travel or examples when an afternoon NAD therapy session could be exceptions.

Are There any Side Effects from Frequent NAD Injections?

Receiving NAD injectionos too frequently can result in some side effects such as difficulty concentrating, And, while excess NAD is excreted naturally through urine, NAD can break down essential molecules for healthy liver functions. Close monitoring by a medical professional is recommended to ensure dosage and frequency of NAD injections are safely used.

How do I Know if NAD is Working for Me?

Depending on your current NAD level, most individuals feel an energy boost within 1-2 hours. Other benefits (anti-aging for example) are more cumulative and results may not be noticeable right away. 

References:

[1] Nature, NAD+ metabolism, stemness, the immune response, and cancer, Navas, L.E., Carnero, A. NAD+ metabolism, stemness, the immune response, and cancer. Sig Transduct Target Ther 6, 2 (2021).

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